时 间：2019年1月6 日（周日）10:00
Brief Introduction of Professor Jianrong Tan
Jianrong Tan,from Huzhou,Zhejiang，is an academician of Chinese Academy of Engineering, Ministry of science and technology "973" project Chief Scientist, “Qiu Shi”special professor and Ph.D. supervisor of Zhejiang University.Working as Director of department design engineering and automation , the dean of the Institute of Robotics of Zhejiang University, Chairman of China big data technology and the Applied Industry Alliance, Vice Chairman of the China Society of Mechanical Engineering, Vice Chairman of the Chinese Society of Graphics, and Director of the Engineering Graphics Teaching Steering Committee of the Ministry of Education, Jianrong Tan successively awarded the “Professional Individual of the Ministry of Science and Technology Fifteen 863”, “Eleventh Five-Year of the Ministry of Science and Technology” National Science and Technology Plan Executive Outstanding Contribution Award, ''National Excellent Science and Technology Worker'' and other honors and titles.
He Mainly engaged in data modeling and virtual reality, digital design and intelligent manufacturing research, won the second prize of the National Science and Technology Progress Award, 7 provincial and ministerial level scientific and technological progress first prize, the teaching achievement won the national outstanding teaching achievement award 3 Among them, 1 first prize and 2 second prize. Obtained 56 registration rights for invention patents and software works.
主讲人：James Fraser Stoddart教授 诺贝尔化学奖获得者
题 目：My Journey to Stockholm
詹皇·弗雷泽·司徒塔特教授于1966年获得爱丁堡大学博士学位，现任美国西北大学教授。是有机超分子化学和纳米科学领域最杰出的科学家之一，迄今已在《Nature》、《Science》、《Nature Nanotechnology》、《Nature Chemistry》等杂志上发表1000余篇学术论文，h-index = 124，科学引文次数世界排名第三。1994年当选英国皇家科学院院士，1999年当选德国自然科学院院士，2006年当选荷兰皇家艺术与科学院外籍院士，同年被英国皇室伊丽莎白二世授予勋爵爵位，2007年因其在分子机器领域的杰出和开创性工作获得了爱因斯坦科学奖。2012年当选美国人文与科学院院士，2014年当选美国科学院院士，2016年获得诺贝尔化学奖， 并入选“外教中国”十大年度人物，2017年当选为中国科学院外籍院士并获2017年度中国政府友谊奖。在司徒塔特教授从事科学研究的40余年期间，他做了1000余场学术邀请报告，成功培养了超过400名博士和博士后，其中80余人任职于国际著名大学。
Brief Introduction of Professor James Fraser Stoddart
Sir James Fraser Stoddart got his PhD at Edinburgh University in 1966 and is Board of Trustees Professor of Chemistry. Sir Fraser is one of the outstanding scientists in area of supramolecular chemistry and nanotechnology. Sir Fraser has published more than 1000 peer reviewed papers on the journal including Nature, Science, Nature Nanotechnology, and Nature Chemistry. As of 2016 Sir Stoddart has an h-index of 124. For the period from January 1997 to 31 August 2007, he was ranked by the Institute for Scientific Information as the third most cited chemist. Sir Fraser was elected as a Fellow of the Royal Society of London in 1994, the Fellowship of Natural Sciences (Leopoldina) of Germany in 1999, and the Foreign membership of Science Division of the Royal Netherlands Academy of Arts and Sciences in 2006. Stoddart was appointed a Knight Bachelor in the New Year's Honours December 2006, by Queen Elizabeth II. In 2007, he received the Albert Einstein World Award of Science in recognition for his outstanding and pioneering work in molecular machines. He was also elected the Fellowship of American Academy of Arts and Sciences in 2012 and the Membership of National Academy of Science, USA in 2014. In 2016 Sir Fraser shared the Nobel Prize in Chemistry together with Ben Feringa and Jean-Pierre Sauvage for the design and synthesis of molecular machines. He was also elected as one of the “International Educator in China Award” in 2016, the Foreign membership of the Chinese Academy of Science in 2017, and one of the winners of “Chinese Government Friendship Award” in 2017. He has given >1,000 plenary/invited lectures. During 45 years, >400 PhD and postdoctoral students have passed through his laboratories and been inspired by his imagination and creativity, and >80 have subsequently embarked upon successful independent academic careers.
Sir Fraser works in the areas of mechanostereochemistry and molecular machine. He creatively developed a new synthetic molecular machine based on molecular mechanical interlocking structure, and put forward the mechanical bond concept different from the traditional chemical valence bond theory, making a landmark contribution to the further development of the field of chemistry. He and Sauvage developed the template synthesis method based on non-covalent bonding, which greatly improved the synthetic efficiency of mechanical interlocking molecular machines. He created prototypes of thermally driven molecular machines, molecular shuttles, and molecular switches that respond to external stimuli. By building an energy ratchet, he designed and synthesized a true molecular machine that could do work on the outside system -- a molecular pump. Sir Fraser also extended the concept of molecular machines to a variety of applications, such as high-density storage devices based on molecular size. In addition, he not only realized the complex topological systems such as the Olympic ring and Borromean ring at the molecular level, but also organically combined supramolecular chemistry and topology, and proposed the concept of "mechanical stereochemistry", which promoted the development of molecular topology in the field of chemistry. His work on molecular machines with relevant scientists opened a new door in the field of chemistry and brought human to the "mechanical civilization" at molecular dimensions.
时 间：2019年1月9日（周三）15 ：00
题 目：Innate immunity to cytosolic bacteria: pyroptosis and beyond
Brief Introduction of Professor Feng Shao
Dr. Feng Shao graduated from the School of Physics at Peking University and received his bachelor degree in Applied Chemistry in 1996, received his master degree in Molecular Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing in 1999, and received his Ph.D. in Biological Chemistry, University of Michigan Medical School, USA. Currently, he is a senior investigator and deputy director at National Institute of Biological Sciences, Beijing.
Dr. Feng Shao’s laboratory is interested in studying the interaction mechanisms of Bacterial pathogens and the host. His laboratory work has led to several a series of important and original discoveries in the pathogenic virulence mechanism and anti-bacterial natural immunity. For instance, the laboratory found that bacterial endotoxin (LPS), flagella and intracellular secretion system of pathogens innate immune receptors (assembled to form inflammatory corpuscle complexes), which in turn reveals and elucidates the exact molecular mechanisms of which inflammatory caspase downstream of these receptors induces cell pyroptosis by shearing and activating Gasdermin D (GSDMD) proteins; these findings provide a new theoretical basis for the development of the sepsis pharmaceuticals and bacterial vaccines, and the elaboration of the identification and mechanism of the Gasdermin family also redefines the concept of cell pyroptosis into a programmed necrosis mediated by the Gasdermin family. Dr. Shao Feng has published more than 70 academic papers, which have been quoted by 9,000 times in total. After returning to China in 2005, he published 13 research papers in the three major journals of Nature, Science and Cell. He won several international and domestic important awards include Zhou Guangzhao Outstanding Youth Foundation Science Award, HHMI International Young Scientist Award, International Protein Society Evansig Young Scientist Award, Wu Jieping & Paul Yangsen Basic Medicine Award, and the He Liang & He Li Fund Science and Technology Award. He was also selected into the High-level Talent Project, National Talent Project, first “Beijing Scholar” and National 10,000 Talents Plan (leading talent), expert for the special allowance of the State Council. He was elected as an academician of the Chinese Academy of Sciences and a foreign member of EMBO in 2015, and was elected as the fellow of the College of Microbiology of United States in 2016.